joint or muscle pain
Metabolism: Naltrexone is metabolized to an active metabolite 6β-naltrexone
Use of VIVITROL should be
Naltrexone is used as an adjunct to social and psychotherapy in the treatment of opioid and alcohol addiction
This means that when it enters the brain it will “knock out” other opioids, such as heroin, that are sitting in the brain’s
It provides opioid blockade by delivering steady naltrexone concentrations for about 1 month
Cost Considerations Alternative drugs Precautions Drug Images Naltrexone is a generic drug that’s prescribed for opioid use disorder and alcohol use disorder
Blood levels
The long-acting properties of naltrexone are due primarily to 6-β-naltrexol, which has an
These side effects may be temporary, lasting a few days to
anxiety or nervousness
ringing or
reduce the tendency to want to drink more 5
Administered every 4 hours; dosage increased in 2-mg increments during the daytime on day 3
Naltrexone therapy is typically given to patients with a high background rate of liver disease (injection drug use or alcoholism) and has been associated with variable rates of serum enzyme elevations (0% to 50%), values above 3 times the upper limit of normal occurring in approximately 1% of patients and occasionally leading
Always use a non-narcotic medicine to treat pain, diarrhea, or a cough
Anyone can give this very fast-acting medication, as a shot or nasal spray
Comments: There is no data specifically addressing switching from buprenorphine or methadone to naltrexone, however some patients have reported
Naltrexone is also approved to help treat alcohol use disorder (AUD), also called alcohol dependence
Other side effects not listed may also occur in
Ann Neurol
the half-life of naltrexone and 6-beta-naltrexol is 5-10 days
A person caring for you should seek emergency medical attention if you have
The first pass of naltrexone’s metabolism is 5–40% oral bioavailability
It’s FDA-approved to treat alcohol use disorder and opioid use disorder
Of the total drug interactions, 34 are major, and 300 are moderate